个人简介

吴振龙，博士，副研究员，硕士生导师。2017年毕业于暨南大学，获医学博士学位，同年进入暨南大学中西医结合博士后流动站，2018年12月赴伊利诺伊大学芝加哥分校访学，2020年进入暨南大学药学院工作。主要从事中药和天然药物的活性成分研究，先后主持国家自然科学基金面上项目、青年科学基金项目、中国博士后科学基金特别资助项目和广东省自然科学基金面上项目等国家和省部级以上项目5项，并作为课题骨干参与国家重点研发计划项目、国家自然科学基金重点项目及NSFC-广东省政府联合基金重点项目等多项，入选王宽诚青年学者；在Angewandte Chemie International Edition、Organic Letters、Chinese Chemical Letters、Chemistry-A European Journal、Journal of Organic Chemistry和Journal of Natural Products等国际权威期刊发表SCI研究论文30余篇；申请中国发明专利3项；参编专著1部。

主要研究方向

1.中药和天然药物的活性成分研究

2.天然生物活性分子高效发现新策略研究

3.中药及天然药物来源的创新药物研究 

代表性论文

1.Wu ZL#, Zhao BX#, Huang XJ, Tang GY, Shi L, Jiang RW, Liu X, Wang Y*, Ye WC*. Suffrutines A and B: a pair of Z/E isomeric indolizidine alkaloids from the roots of Flueggea suffruticosa. Angewandte Chemie-International Edition, 2014, 53: 5796. 

2.He QF#, Wu ZL#, Li L, Sun WY, Wang GY, Jiang RW, Hu LJ, Shi L, He RR, Wang Y*, Ye WC*. Discovery of neuritogenic Securinega alkaloids from Flueggea suffruticosa by a building-block-based molecular network strategy. Angewandte Chemie-International Edition, 2021, 60: 19609. 

3. Wu ZL#, Huang XJ#, Hu LJ#; Zhang WY, Xie QJ, Jiang RW, Wang Y*, Ye WC*. Absolute configurations and stereochemical inversion mechanism of epimeric Securinega alkaloids from Flueggea suffruticosa. Organic Letters, 2020, 22: 3673. 

 4.Wu ZL#, Huang XJ#, Xu MT, Ma X, Li L, Shi L, Wang WJ, Jiang RW, Ye WC*, Wang Y*. Flueggeacosines A-C, dimeric securinine-type alkaloid analogues with neuronal differentiation activity from Flueggea suffruticosa. Organic Letters, 2018, 20: 7703. 

5.He QF#, Wu ZL#, Huang XJ, Zhong YL, Li MM, Jiang RW, Li YL, Ye WC*, Wang Y*. Cajanusflavanols A-C, three pairs of flavonostilbene enantiomers from Cajanus cajan. Organic Letters, 2018, 20: 876. 

6.Zhang JY#, Liu F#, Jin Q, Li XY, Zhan Q, Chen M, Wang S, Wu ZL*, Ye WC*, Wang L*. Discovery of unusual phloroglucinol–triterpenoid adducts from Leptospermum scoparium and Xanthostemon chrysanthus by building blocks-based molecular networking. Chinese Chemical Letters, 2024, 35: 108881. 

 7.Wu ZL#, Zhang WY#, Zhong JC, Huang XJ, Xu W, Chen MF, Weng SQ, Zhang DM, Che CT*, Ye WC*, Wang Y*. Angiogenesis-inhibitory piperidine alkaloids from the leaves of Microcos paniculata. Journal of Natural Products, 2022, 85: 375. 

8.Liu H#, Wu ZL#, Huang XJ, Peng Y, Huang X, Shi L, Wang Y*, Ye WC*. Evaluation of diarylheptanoid-terpene adduct enantiomers from Alpinia officinarum for neuroprotective activities. Journal of Natural Products, 2018, 81: 162. 

9.He QF#, Wu ZL#, Huang XJ, Xia TQ, Tang G, Tang W, Shi L, Ye WC*, Wang Y*. Cajanusoids A-D, unusual atropisomeric stilbene dimers with PTP1B inhibitory activities form the leaves of Cajanus cajan.  Journal of Organic Chemistry, 2021, 86: 5870. 

10.Li ZW, Fan C L, Sun B, Huang L, Wang ZQ, Huang XJ,Zhang SQ, Ye WC*, Wu ZL*, Zhang XQ*. Discovery of unusual ajmaline‐macroline type bisindole alkaloids from Alstonia macrophylla by building blocks‐based molecular networking. Chemistry–A European Journal, 2024, 30: e202303519.  

11.Tan LX#, Xia TQ#, He QF, Tang W, Huang XJ, Song QY, Li Y L, Ye WC*, Wang Y*, Wu ZL*. Stilbenes from the leaves of Cajanus cajan and their in vitro anti-inflammatory activities. Fitoterapia, 2022, 160: 105229. 

12.Yang WQ#, Tang W#, Huang XJ, Song JG, Li YY, Xiong Y, Fan CL, Wu ZL*, Wang Y*, Ye WC. Quassinoids from the roots of Eurycoma longifolia and their anti-proliferation activities. Molecules, 2021, 26: 5939.