个人简介

刘芬，博士后，主要从事中药及天然药物活性成分的研究，同时也涉及新型功能天然分子的快速发现、中药制剂和食品成分分析、药材质量标准建立等领域。在对金娘科蜜源植物金蒲桃、松红梅、海洋动物珊瑚和珊瑚共附生微生物等多种天然产物活性成分研究过程中，发现了200余个天然化合物（其中新化合物100余个、新骨架结构化合物40余类）及一些新药先导化合物和新型功能天然分子。

主要学术和科研成绩：已发表研究论文14篇，以第一作者（含共一）在Chinese Chemical Letters、Journal of Organic Chemistry、Chemistry ＆ Biodiversity等期刊发表SCI论文8篇；主持国家自然科学基金青年科学基金项目1项，参与国家自然科学项目4项。

研究方向

1. 中药及天然药物活性成分研究

代表性论文

1.Zhang Jin-Yan1, Liu Fen1, Jin Qian, Li Xue-Yi, Zhan Qiong, Chen Mu, Wang Si-Si, Wu Zhen-Long*, Ye Wen-Cai*, Wang Lei*. Discovery of unusual phloroglucinol–triterpenoid adducts from Leptospermum scoparium and Xanthostemon chrysanthus by building blocks-based molecular networking. Chinese Chemical Letters, 2023: 108881. (IF=9.1）

2.Liu Fen1, Tian Hai-Yan1, Huang Xiao-Lin, Wang Wen-Jing, Li Ni-Ping, He Jun, Ye Wen-Cai*, Wang Lei*. Xanthchrysones A-C: rearranged phenylpropanoyl-phloroglucinol dimers with unusual skeletons from Xanthostemon chrysanthus. Journal of Organic Chemistry, 2019, 84(23): 15355-15361. 

3.Liu Fen1, Chen Mei-Hong1, Hu Yan-Xia, Zhan Qiong, Zhang Jin-Yan, ZhangZi-Yue, Wang Si-Si, Ye Wen-Cai*, Wang Lei*. Xanchryones I-N, six unusual phloroglucinol-amino acid hybrids from the leaves of Xanthostemon chrysanthus. Chemistry ＆ Biodiversity, 2023, 20(4): e202300234.

4.Liu Fen1, Wu Yan1 Li Ni-Ping, Liu Jiao-Wen, Wang Lei*, Ye Wen-Cai*. Chiral isolation and absolute configuration of (+)- and (-)-xanchryones F and G from Xanthostemon chrysanthus. Chemistry ＆Biodiversity, 2020, 17(1): e1900683. 

5.Liu Fen, Lu Wei-Jin, Li Ni-Ping, Liu Jiao-Wen, He Jun, Ye Wen-Cai*, Wang Lei*. Four new cinnamoyl-phloroglucinols from the leaves of Xanthostemon chrysanthus. Fitoterapia, 2018, 128: 93-96. 

6.Sun Huan1, Liu Fen1, Feng Mei-Ran, Peng Qi, Liao Xiao-Jian, Liu Ting-Ting, Zhang Jun*, Xu Shi-Hai*. Isolation of a new cytotoxic polyhydroxysterol from the South China Sea soft coral Sinularia sp.. Natural Product Research, 2016, 30(24): 2819-2824.

7.Peng Qi1, Liu Fen1, Sun Huan, Liao Xiao-Jian, Feng Mei-Ran, Liu Ting-Ting, Xu Zheng-Xiong, Zhang Jun*, Xu Shi-Hai*. A new sesquiterpene from the gorgonian coral Menella sp.. Natural Product Research, 2016, 30(20): 2299-2304. 

8.Liu Fen, Li Shuo, Ju Zhi-Ran, Liu Ting-Ting, Liang Rui-Yu, Liao Xiao-Jian, Xu Shi-Hai*. N-(3-aminopropyl)subergorgamide, a new alkaloid from the gorgonian Paraplexaura sp.. Journal of Asian Natural Products Research, 2015, 17(8): 851-855.