个人简介
胡利军，理学博士，副研究员、硕士生导师，2018年毕业于中国药科大学天然药物化学专业，获博士学位，导师为叶文才教授。在硕博连读期间，先后于北京大学深圳研究生院和南方科技大学李闯创教授课题组从事天然产物全合成研究工作。2020于暨南大学中药学博士后流动站完成博士后研究工作。2021年入职暨南大学药学院。本人主要围绕活性天然产物的仿生合成和成药性修饰方向开展研究工作。目前，主持国家自然科学基金青年基金、广东省自然科学基金面上项目和青年提升项目、中国博士后科学基金面上项目各1项，并作为项目骨干获广东省重点领域研发计划和广东省区域联合基金重点项目各1项；申请发明专利10项，其中授权6项和申请PCT专利3项；已在Angewandte Chemie International Edition、Organic Letters (2篇)、Organic Chemistry Frontiers (2 篇)、Chemistry A European Journal、Journal of Organic Chemistry等本专业领域国际权威期刊发表SCI论文16篇，其中以第一/共一作者或共同通讯作者发表论文8篇。
研究方向
1.活性天然产物的仿生合成研究
2.活性天然产物的成药性修饰研究
代表性论文
1.Wang J#, Song JG#, Zhong DL, Duan ZZ, Peng ZJ, Tang W, Song QY, Huang XJ, Hu LJ*, Wang Y*, Ye WC*. Biomimetic Synthesis of an Antiviral Cinnamoylphoroglucinol Collection from Cleistocalyx operculatus: A synthetic Strategy Based on Biogenetic Building Blocks, Angewandte Chemie International Edition, 2023, 62: e202312568.
2.Deng LM#, Tang W#, Wang SQ, Song JG, Huang XJ, Zhu HY, Li YL, Ye WC*, Hu LJ*, Wang Y*. Discovery and Biomimetic Synthesis of a Polycyclic Polymethylated Phloroglucinol Collection from Rhodomyrtus tomentosa, The Journal of Organic Chemistry, 2022, 87: 4788–4800.
3.Deng LM#, Hu LJ#, Bai YTZ, Wang J, Qin GQ, Song QY, Su JC, Huang XJ, Jiang RW, Tang W, Li YL, Li CC*, Ye WC*, Wang Y*. Rhodomentosones A and B: Two Pairs of Enantiomeric Phloroglucinol Trimers from Rhodomyrtus tomentosa and Their Asymmetric Biomimetic Synthesis, Organic Letters, 2021, 23: 4499–4504.
4.Deng LM#, Hu LJ#, Tang W#, Liu JX, Huang XJ, Li YY, Li YL, Ye WC*, Wang Y*. A Biomimetic Synthesis-enabled Stereochemical Assignment of Rhodotomentones A and B, Two Unusual Caryophyllene-derived Meroterpenoids from Rhodomyrtus tomentosa, Organic Chemistry Frontiers, 2021, 8: 5728–5735.
5.Wu ZL#, Huang XJ#, Hu LJ#, Zhang WY, Xie QJ, Jiang RW, Wang Y*, Ye WC*. Absolute Configurations and Stereochemical Inversion Mechanism of Epimeric Securinega Alkaloids from Flueggea suffruticosa. Organic Letters, 2020, 22: 3673-3678.
6.Luo SL#, Hu LJ#, Huang XJ, Su JC, Shao XH, Wang L, Xu HH, Li CC*, Wang Y*, Ye WC*. Discovery and Biomimetic Synthesis of a Phloroglucinol-Terpene Adduct Collection from Baeckea frutescens and Its Biogenetic Origin Insight, Chemistry-A European Journal, 2020, 26: 11104–11108.
7.He J#, Hu LJ#, Huang XJ#, Wang CR, Zhang ZM, Wang Y, Zhang DM*, Ye WC.* Potential of Coronavirus 3C-like Protease Inhibitors for the Development of New Anti-SARS-CoV-2 Drugs: Insights from Structures of Protease and Inhibitors. International Journal of Antimicrobial Agents, 2020, 56: 106055.
8.Hu LJ#, Cheng MJ#, Cao JQ, Zhong LP, Hu YJ, Wang Y, Wang L*, Ye WC*, Li CC.* Asymmetric Total Syntheses of Callistrilones B, G and J. Organic Chemistry Frontiers, 2018, 5 (9), 1506–1510.
